Lab

Samy Meroueh
Assistant Professor
Department of Biochemistry and Molecular Biology
(317) 274-8315
smeroueh@iupui.edu
Meroueh Lab

Assistant Professor of Biochemistry and Molecular Biology. Samy Meroueh studied chemistry at Wayne State University where he received his Ph.D. under the supervision of William L. Hase. He then joined the group of Shahriar Mobashery as a Walther Cancer Institute Fellow at the University of Notre Dame in South Bend, Indiana. During his tenure in the Mobashery lab he used computational and experimental tools towards understanding the catalytic machinery of enzymes that are involved in antimicrobial resistance and various pathological processes such as cancer. He was also involved in the design and discovery of molecules that would target those enzymes as potential therapeutic agents. His current interests lie in the development and implementation of a more robust scoring function for the purpose of virtual screening, and the use of this scoring function in the search of small molecules that would disrupt macromolecular interactions for the discovery of lead molecules with the potential of becoming clinically relevant. Surface plasmon resonance, isothermal titration calorimetry, as well as various computational tools will be used to characterize the kinetics and thermodynamics of binding for these compounds. His research will focus on three targets, namely the urokinase plasminogen activator system, the bacterial sortases, and the acyltransfer site of the bacterial ribosome.

Agnes Alvarez
aalvarez@iupui.edu

Jason Baird
jpbaird@iupui.edu

Jesse Bright
bright3@iupui.edu

Jing Li
Research Technician
Biochemistry and Molecular Biology
li46@iupui.edu

Liwei Li
Postdoctoral Associate
liwei.li@gmail.com

Louay Meroueh

Meaghan Pilcher
mpilcher@iupui.edu