IG-Browser is an imaging genomic browsing system designed for genome wide analysis of neuroimaging phenotypes. The system is still under development. Some results created by our prototype tool are available here.

References

Kim S, Shen L, Saykin AJ, and West JD. Visual exploration of genetic association with voxel-based imaging phenotypes in an MCI/AD study. EMBC'09: the 31st Annual Int. Conf. of the IEEE Engineering in
Medicine and Biology Society, September 2-6, 2009, Minneapolis, Minnesota.

Shen L, Kim S, West JD, Saykin AJ. Building an imaging genomic browsing system for examining genetic effects on brain. OHBM’09: 15th Annual Meeting of Organization for Human Brain Mapping, selected for oral presentation, June 18 - 23, 2009, San Francisco, CA.

Kim S, Shen L, Saykin AJ, and West JD. Data synthesis and tool development for exploring imaging genomic patterns. CIBCB'09: IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, 3/30-4/2, 2009, Nashville, TN.

SPHARM-MAT is a matlab-based 3D shape modeling and analysis toolkit for neuroanatomical studies, and is designed to aid statistical shape analysis for identifying morphometric changes in brain structures related to neuropsychiatric disorders. The project is supported by NIBIB/NEI R03EB008674-01. We expect to release SPHARM-MAT at NITRC in the end of 2009.

References

Shen L, Kim S, Saykin AJ. Fourier method for large scale surface modeling and registration. Computers and Graphics (Special Issue on Shape Modeling International 2009), 33(3):299-311.

Shen L, Firpi HA, Saykin AJ, West JD. Parametric surface modeling and registration for comparison of manual and automated segmentation of the hippocampus. Hippocampus (Special Issue on Computational Anatomy and Physiology of the Hippocampus), Apr 29, 2009. [Epub ahead of print]

Shen L, Farid H, and McPeek MA. Modeling 3-dimensional morphological structures using spherical harmonics. Evolution, 63(4):1003-1016, 2009.

Shen L, Huang H, Makedon FS, and Saykin AJ. Efficient registration of 3D SPHARM surfaces. CRV 2007: Fourth Canadian Conference on Computer and Robot Vision, Montreal, QC, pages 81-88, May 28-30, 2007.

Shen L and Chung MK. Large-scale modeling of parametric surfaces using spherical harmonics. IEEE 3DPVT 2006: Third International Symposium on 3D Data Processing, Visualization and Transmission, UNC, Chapel Hill, USA, June 14-16, 2006.

Shen L, and Makedon FS. Spherical mapping for processing of 3-D closed surfaces. Image and Vision Computing, 24(7): 743-761, 2006.