Welcome to the Laboratory of Li Shen at the Indiana University School
of Medicine. Our lab is focused on research and training in medical
image computing and bioinformatics. We study computational and
informatics methods for analyzing structural, functional, diffusion MRI
data and relating them to genomic, clinical, neuropsychiatric and other
biomarker data, with applications to various brain disorders including
Alzheimer’s disease (AD), schizophrenia, multiple sclerosis, and
others. A major current emphasis is on developing methods for bridging
neuroimaging and genomics (e.g., identifying genetic risk factors using
imaging as phenotypes) with particular application to MCI and early AD.
Keywords describing our research areas include medical image computing,
shape modeling and surface morphometry, imaging genomics and
bioinformatics, and machine learning and pattern classification.